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How Azithromycin Works in the Body - Dosepharmacy

11/06/2024 07:14  

Azithromycin, a widely prescribed antibiotic, exerts its therapeutic effects by targeting bacterial infections. This macrolide antibiotic inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of susceptible microorganisms, thereby preventing the translation of mRNA into proteins crucial for bacterial survival and replication.

Once ingested, Azithromycin is rapidly absorbed from the gastrointestinal tract, reaching peak plasma concentrations within two to three hours. It has a long half-life, allowing for once-daily dosing convenience in many cases. The drug distributes extensively throughout the body, reaching therapeutic levels in various tissues and fluids, including lung tissue, making it effective in treating respiratory infections.

Azithromycin's mechanism of action makes it effective against a wide range of bacteria, including respiratory pathogens like Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. It is also active against sexually transmitted infections such as Chlamydia trachomatis and Neisseria gonorrhea.

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Reference: BM-PROP-2024-06-1053
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